Test Entry - Detail

Alpha Fetoprotein (Amniotic Fluid)

General

Clinical Use:

Alpha Fetoprotein is an embryonic-specific protein synthesised by the fetal liver. It reaches the amniotic fluid via the fetal urine then diffuses across the amniotic membrane to the maternal blood. The level of AFP in amniotic fluid is increased in connection with fetal malformations, especially neural tube defects. Other conditions giving increased levels incluse spontaneous abortion, fetal distress or death, oligohydramnio, gastroschisis, Meckel's syndrome, sacrococcylgeal,teratoma and Turner's syndrome.

Availability:

Samples are tested Monday-Friday.

Aliases/Synonyms:

AFP (Amniotic Fluid), Amniotic Fluid AFP,

Code:

AFAFP

Handling Instructions (to laboratory):

Send sample chilled.

Hyperlink:

Reference Interval:

Gestation     97th centile
(weeks)
13            27 kU/mL
14            24 kU/mL
15            21 kU/mL
16            20 kU/mL
17            17 kU/mL
18            15 kU/mL
19            12 kU/mL
20            10 kU/mL
21            10 kU/mL
22            8 kU/mL

Collection Requirements

Container:

Sterile Container (STERILE),

Sample Type:

See container

Minimum Collection Volume:

200uL

Collection Instructions:

Processing Requirements

Alternate Containers:

Processing Instructions:

Sample preparation is performed by the cytogenetics department at KEMH.

Minimum Assay Volume:

200uL

Stability:

6 days chilled

Transport Instructions (to testing laboratory):

Send sample chilled.

Testing Locations

Performed at:

Section	Department	Site	Contact Phone
Special Chemistry	Biochemistry	QEII Medical Centre	6383 4114

Last Updated : 16-01-2024 10:59