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General
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Clinical Use:
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In normal individuals beta-2-microglobulin is found in both the serum and the urine. Serum levels of beta-2-microglobulin are a function of its rate of synthesis or it's rate of release into the circulation. Serum levels are frequently increased in inflammatory disorders (eg rheumatoid arthritis, Sjogrens Syndrome and Crohn's diease) and in lymphoproliferative diseases( eg. multiple myeloma, B cell lymphoma and chronic lymphocytic leukaemia) In the lymphoproliferative diseases beta-2-microglobulin is often used as a measure of the tumour load. Serum levels are also elevated as a result of decreased clearance in renal insufficiency and are negatively correlated to creatinine clearance. |
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Availability:
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Samples are tested Monday-Friday. |
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Aliases/Synonyms:
| B2M, |
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Code:
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B2M |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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to 30 days <4.5
to 6 months <3.5
to 12 months <3.0
to 7 years <2.5
to 19 years <2.0
> 19 years <2.9
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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1mL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Lithium Heparin-PST (GREEN) |
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Processing Instructions:
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Centrifuge sample as soon as possible. |
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Minimum Assay Volume:
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200uL |
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Stability:
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7 days chilled; 2 weeks frozen |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Special Chemistry |
Biochemistry |
Fiona Stanley Hospital |
6152 2830 |
| Special Chemistry |
Biochemistry |
QEII Medical Centre |
6383 4114 |
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Last Updated : 19-10-2021 19:54 |