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General
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Clinical Use:
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Caffeine is an effective inhibitor of apnoea and it has a long half- life in premature infants (40 to 230 hrs) compared to adults (3 hrs). Caffeine is metabolised by CyP1A2 and this enzyme is not active in neonates. This explains why a lower therapeutic concentration is needed in neonatal infants. Caffeine is a minor metabolite of theophylline in adults. |
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Availability:
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As required |
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Code:
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CAF |
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Handling Instructions (to laboratory):
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Send sample chilled.
Deliver sample to laboratory as soon as possible. |
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Hyperlink:
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Reference Interval:
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Neonatal caffeine 5 to 30 mg/L.
Toxic range >50mg/L.
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Collection Requirements
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Container:
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Lithium Heparin-PST (GREEN), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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0.2mL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Serum Sep. Tube-SST (GOLD) |
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Processing Instructions:
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Process sample immediately on arrival in laboratory.
The testing department should be contacted to arrange collection of sample from CSRA. After hours deliver sample to Duty Biochemistry Scientist. |
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Minimum Assay Volume:
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0.1mL |
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Stability:
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7 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Special Chemistry |
Biochemistry |
QEII Medical Centre |
6383 4114 |
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Last Updated : 03-10-2020 08:12 |