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B-Type Natriuretic Peptide
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General
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Clinical Use:
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The natriuretic peptide system includes atrial natriuretic peptide (ANP) and B-type natriuretic peptide of myocardial cell origin and C-type natriuretic peptide (CNP) of endothelial cell origin. The cardiac natriuretic peptides promote natriuresis and diuresis, act as vasodilators, and exert antimitogenic effects on cardiovascular tissues. ANP and BNP are secreted by the heart in response to haemodynamic stress. Increased levels of BNP are produced mainly in response to left ventricular wall stretch and volume overload. Measurement of plasma BNP is used as an aid in the diagnosis and assessment of the severity of heart failure. Patient survival following myocardial infarction can be predicted with this test in conjunction with other known risk factors |
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Availability:
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Samples are tested routinely during the testing laboratory's hours of operation. |
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Aliases/Synonyms:
| BNP, Brain Natriuretic Peptide, |
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Code:
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BNP |
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Handling Instructions (to laboratory):
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Send separated sample chilled within 24 hours of collection or frozen on dry ice if transport will be delayed. |
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Hyperlink:
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Reference Interval:
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BNP <100 ng/L
Congestive heart failure (CHF) unlikely
BNP 100-500 ng/L
Equivocal range
BNP >500 ng/L
Consistent with the diagnosis of CHF
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Collection Requirements
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Container:
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EDTA (LAVENDER), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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1mL |
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Collection Instructions:
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If sample will not reach laboratory within 4 hours of collection, it must be centrifuged and separated. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Centrifuge and separate sample within 4 hours of collection. |
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Minimum Assay Volume:
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165uL |
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Stability:
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4 hours ambient (Unseparated EDTA); 24 hours chilled (Separated Plasma); 3 months frozen |
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Transport Instructions (to testing laboratory):
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Send separated sample chilled within 24 hours of collection or frozen on dry ice if transport will be delayed. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Laboratory |
Busselton Hospital |
9753 6260 |
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Laboratory |
Kununurra Hospital |
9166 4245 |
| Core |
Biochemistry |
Fiona Stanley Hospital |
6152 8140 |
| Core |
Biochemistry |
QEII Medical Centre |
6383 4093 |
| Core |
Biochemistry |
Royal Perth Hospital |
9224 1176 |
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Last Updated : 09-10-2024 09:34 |