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General
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Clinical Use:
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Electrophoresis is used to identify the presence or absence of abnormal proteins and to identify when different groups of proteins are increased or decreased in serum. It is frequently used to detect and identify monoclonal proteins. Serum and urine protein electrophoresis are used to help detect, diagnose, and monitor the course and treatment of conditions associated with these abnormal proteins, including multiple myeloma and a few related diseases.
Protein electrophoresis may be requested when investigating symptoms that suggest multiple myeloma, such as bone pain, anaemia, tiredness, unexplained fractures, and recurrent infections. It may also be used as a follow-up to other laboratory tests, such as an abnormal total protein and/or increased globulins level, elevated urine protein levels, elevated calcium levels, and low white or red blood cell counts.
It is recommended that a spot urine for Bence Jones protein also be requested for exclusion of monoclonal gammopathy. |
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Availability:
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Samples are tested Monday-Friday. |
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Aliases/Synonyms:
| Electrophoresis Protein, M Protein, Myeloma Screen, Paraproteins, Protein Electrophoresis , Quantitative Electrophoresis of Protein, Serum Protein Electrophoresis, SPE, |
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Code:
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SPE |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Total Protein
0d -<31d 50 - 70
31d - <1y 55 - 75
1y - <4y 58 - 78
4y - <120y 60 - 80
Albumin
0d -<31d 25 - 40
31d - <17y 32 - 48
17y - <120y 35 - 50
Age Alpha-1-Globulin Alpha-2-Globulin Beta Globulin Gamma Globulin
0d-<6m 2-5 5-10 3-7 2-7
6m-<1y 2-4 6-12 4-8 3-9
1y-<2y 2-4 7-12 5-8 4-10
2y-<7y 2-4 6-11 5-9 5-12
7y-<16y 2-4 5-10 5-9 6-14
16y-<120y 2-4 5-9 6-10 8-16
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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0.5mL |
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Collection Instructions:
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Specify if a paraprotein is suspected or if a known paraprotein requires quantitation on request form. |
Processing Requirements
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Alternate Containers:
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Serum, no gel (RED) |
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Processing Instructions:
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Minimum Assay Volume:
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60uL |
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Stability:
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7 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Special Chemistry |
Biochemistry |
Fiona Stanley Hospital |
6152 2830 |
| Special Chemistry |
Biochemistry |
QEII Medical Centre |
6383 4114 |
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Last Updated : 21-12-2021 13:48 |