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HIV Drug Resistance Genotyping
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General
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Clinical Use:
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During the course of HIV infection the replicating viral genome undergoes constant change. These changes, also known as sequence polymorphisms within drug targets (viral reverse transcriptase, HIV protease, integrase and HIV polymerase) can lead to resistance against anti-retroviral therapies. The sequencing is performed to determine if mutations associated with drug resistance have occurred.
HIV Resistance Genotyping includes HIV Reverse Transcriptase, Integrase and Protease genotyping. |
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Availability:
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Samples are batched and tested once a week. |
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Aliases/Synonyms:
| HIV Integrase Genotyping, HIV Protease Genotyping, HIV Reverse Transcriptase, |
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Code:
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IHGTR |
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Handling Instructions (to laboratory):
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Send whole sample ambient within 6 hours of collection.
Send separated sample frozen on dry ice. |
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory
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Collection Requirements
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Container:
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EDTA (LAV9), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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9mL |
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Collection Instructions:
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If sample will not reach laboratory within 6 hours of collection, it must be centrifuged at 800-1600g for 20 minutes, separated and frozen. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Centrifuge sample at 800-1600g for 20 minutes. Separate and freeze. |
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Minimum Assay Volume:
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500uL |
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Stability:
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6 hours ambient (unseparated) |
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Transport Instructions (to testing laboratory):
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Send separated sample frozen on dry ice. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Immunogenetics Molecular |
Immunology |
Fiona Stanley Hospital |
6152 8006 |
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Last Updated : 01-09-2022 11:42 |