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HLA Typing for Carbamazepine Hypersensitivity
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General
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Clinical Use:
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A strong association exists between HLA B*1502 and carbamazepine (CBZ) associated Stevens-Johnson Syndrome/toxic epidermal necrosis (SJS/TEN) in Han Chinese and some other SE Asian populations where the negative predicive value is >99%.
In Caucasian, Japanese and other non-Asian populations the negative predictive value is significantly less than 99%. |
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Availability:
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As required. |
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Aliases/Synonyms:
| B*1502 Typing, Carbamazepine Hypersensitivity Typing, |
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Code:
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ICAR |
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Handling Instructions (to laboratory):
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Send sample ambient. |
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory
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Collection Requirements
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Container:
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Acid Citrate Dextrose (ACD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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10mL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Store sample at room temperature. |
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Minimum Assay Volume:
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10mL |
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Stability:
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2 days ambient |
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Transport Instructions (to testing laboratory):
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Send sample ambient. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Immunogenetics Molecular |
Immunology |
Fiona Stanley Hospital |
6152 8006 |
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Last Updated : 19-08-2022 11:24 |