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JAK2 Exon 12 Mutation Study
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General
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Clinical Use:
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Detection of JAK2 exon 12 mutations are highly suggestive of polycythaemia vera and are present in approximatly 3% of cases (the majority of JAK2 V617F negative cases).
Note, the absence of this mutation does not exclude an MPN.
This assay is not a front line test and JAK2 V617F mutation studies must be performed in the first instance. Patients with low EPO levels and are JAK2 V617F will be tested. It will not be performed for minimal residual disease detection.
Test can be added on to JAK2 V617F request. |
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Availability:
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Samples are batched and tested once a week. |
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Code:
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HJE12 |
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Handling Instructions (to laboratory):
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Send sample ambient. |
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Hyperlink:
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Reference Interval:
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Collection Requirements
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Container:
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EDTA (LAVENDER), |
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Sample Type:
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Blood; Bone Marrow |
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Minimum Collection Volume:
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Store sample ambient. |
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Minimum Assay Volume:
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3mL Blood; 1mL Bone Marrow |
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Stability:
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Transport Instructions (to testing laboratory):
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Send sample ambient. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Molecular |
Haematology |
Fiona Stanley Hospital |
6152 8118 |
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Last Updated : 11-07-2024 09:54 |