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Vasoactive Intestinal Peptide
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General
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Clinical Use:
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Vasoactive Intestinal Peptide (VIP) is a member of the secretin-glucaon family; highest concentrations are found in the gut and nervous system. The main effects of VIP include relaxation of smooth muscle (bronchial and vascular dilation), stimulation of gastrointestinal water and electrolyte secretion, and release of pancreatic hormones.
Measurement of VIP concentrations is useful to screen for VIP-secreting tumours (VIPoma), to detect occult metastases and to evaluate surgical or drug therapies. Hypersecretion of VIP is believed to result in Verner-Morrison syndrome (pancreatic cholera syndrome) - watery diarrhoea with hypokalemia and achlorhydria. |
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Availability:
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Aliases/Synonyms:
| VIP, |
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Code:
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VAIP |
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Handling Instructions (to laboratory):
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Send separated sample frozen on dry ice. |
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Hyperlink:
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Reference Interval:
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Fasting adult: 0 - 50 pmol/L
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Collection Requirements
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Container:
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VIP/Glucagon (VIP/GLUC), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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5mL |
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Collection Instructions:
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Patient must be fasting.
Refer to Duty Biochemist prior to collection of sample.
Special tube available from QEII CSRA.
Sample must be centrifuged, separated and frozen immediately following collection. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Centrifuge, separate and freeze sample. |
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Minimum Assay Volume:
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1mL |
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Stability:
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Transport Instructions (to testing laboratory):
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Send separated sample frozen on dry ice. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Laboratory |
Sullivan Nicolaides |
(07) 3377 8666 |
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Last Updated : 03-09-2024 12:48 |