|
|
General
|
| |
Clinical Use:
|
Prealbumin/Transthyretin is an unglycosylated protein that transports the thyroid hormones triiodothyronine (T3), thyroxine (T4) and retinol. Prealbumin is synthesized in the liver and due to its short half-life of approximately 2 days; it can be used for monitoring the nutritional status and efficacy of parenteral nutrition (nutrition from outside of the gastrointestinal tract). Prealbumin is also a negative acute-phase reacting protein; consequently levels decrease rapidly in inflammatory states, despite adequate nutritional stores.
Prealbumin/Transthyretin can also be associated with a form of amyloidosis. As amino acid substitutions in the transthyretin (TTR) gene leads to unstable, amyloidogenic TTR protein deposits in the body. |
| |
Availability:
|
|
| |
Aliases/Synonyms:
| Transthyretin, |
| |
Code:
|
PALB |
| |
Handling Instructions (to laboratory):
|
Send sample chilled. |
| |
Hyperlink:
|
|
| |
Reference Interval:
|
0.17 - 0.35 g/L
|
Collection Requirements
|
| |
Container:
|
Serum Sep. Tube-SST (GOLD), |
| |
Sample Type:
|
See container |
| |
Minimum Collection Volume:
|
1mL |
| |
Collection Instructions:
|
|
Processing Requirements
|
| |
Alternate Containers:
|
|
|
|
|
Serum, no gel (RED) |
| |
Processing Instructions:
|
Centrifuge and separate sample. |
| |
Minimum Assay Volume:
|
500uL |
| |
Stability:
|
|
| |
Transport Instructions (to testing laboratory):
|
Send sample chilled.
Requests should be reviewed by Duty Biochemist prior to transport. |
Testing Locations
|
| |
Performed at:
|
|
Section
|
Department
|
Site
|
Contact Phone
|
| - |
Laboratory |
SSWPS-Royal Prince Alfred Hospital |
(02) 9515 8279 |
|
Last Updated : 19-12-2025 11:42 |