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General
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Clinical Use:
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Pathology in cryofibrinogenaemia is thought to be secondary to thrombotic occlusion of medium and small arteries with features of vasculitis, most commonly cutaneous ischaemia including purpura, livedo reticularis, ulceration and necrosis. Cryofibrinogens may be primary ('idiopathic') or more commonly secondary to underlying inflammatory condition such as infection, malignancy or connective tissue disease. Cryofibrinogens may occasionally be seen in normal healthy individuals, usually at low levels. Cryofibrinogens cannot be assesed without a corresponding Cryoglobulin (serum) sample. |
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Availability:
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Samples are tested Monday-Friday. |
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Code:
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CRYFB |
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Handling Instructions (to laboratory):
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Deliver sample at 37 degrees to laboratory within 2 hours of collection. |
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Hyperlink:
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Reference Interval:
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Not Detected
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Collection Requirements
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Container:
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EDTA x 5 (LAVENDER), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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20mL (>12 years); 5mL (<12 years) |
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Collection Instructions:
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Please also refer to collection of Cryoglobulins as these 2 tests are performed together.
Preferable that patient is fasting. (Lipid can interfere with the assay).
Pre-warm needle, syringe and blood tubes to 37 degrees.
Collect sample and incubate at 37 degrees.
Samples must be incubated for 2 hours at 37 degrees and centrifuged at 37 degrees.
Separated samples may be kept and transported at room temperature.
Samples must be delivered to the testing laboratory before 2pm Monday-Friday ONLY. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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The testing department should be contacted to arrange collection of sample from CSRA.
If sample has been chilled, it must remain at 4 degrees for duration of testing. |
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Minimum Assay Volume:
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4mL |
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Stability:
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2 hours at 37 degrees; |
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Transport Instructions (to testing laboratory):
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Send separated sample ambient. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Immunology |
Fiona Stanley Hospital |
6152 8006 |
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Immunology |
QEII Medical Centre |
6383 4306 |
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Last Updated : 12-06-2025 09:48 |