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General
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Clinical Use:
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Detection of somatic mutations in exons 12, 14 and 18 of the PDGFRA gene in gastrointestinal stromal tumours (GISTs) is used to select patients suitable (or unsuitable)for treatment with tyrosine kinase inhibitor (TKI) drugs (eg imatinib, Gleevec). |
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Availability:
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Samples are tested routinely during the testing laboratory's hours of operation. |
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Aliases/Synonyms:
| Platelet Derived Growth Factor Receptor A, |
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Code:
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HST |
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Handling Instructions (to laboratory):
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Send fresh samples chilled.
Send fixed samples ambient. |
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Hyperlink:
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Reference Interval:
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Not Applicable
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Collection Requirements
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Container:
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Sterile Container (STERILE), |
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Sample Type:
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Tissue |
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Minimum Collection Volume:
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N/A |
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Collection Instructions:
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Fresh samples should be placed into a sterile container without fixative.
Fixed samples should be placed into sufficient 10% Buffered Neutral Formalin to completely submerge the sample.
Contact testing laboratory for further instructions. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Refer to local manual for processing requirements. |
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Minimum Assay Volume:
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N/A |
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Stability:
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Transport Instructions (to testing laboratory):
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Send fresh samples chilled.
Send fixed samples ambient. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Molecular Pathology |
Anatomical Pathology |
QEII Medical Centre |
6457 2679 |
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Last Updated : 30-01-2024 10:01 |