Test Entry - Detail

Urine Porphobilinogen

General

Clinical Use:

Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms.

Availability:

Samples are batched and tested once a week.
Any urgent requests must be authorised by the Duty Biochemist.

Aliases/Synonyms:

PBG, Porphyrin-Porphobilinogen ,

Code:

UPN

Handling Instructions (to laboratory):

Send sample chilled and protected from light.

Hyperlink:

Reference Interval:

FOR "NORMAL" RESULTS <1.5µMOL/MMOL CREATININE:
"A normal porphobilinogen result excludes acute porphyria only if the urine was collected while the patient was symptomatic."

RESULTS BETWEEN 1.5 AND 10.0 µMOL/MMOL CREATININE:
"This porphobilinogen result falls in an equivocal range and should be followed up with a repeat random urine sample"

RESULTS >10.0 µMOL/MMOL CREATININE:
"This porphobilinogen result is considered significantly elevated and is diagnostic for acute porphyria"

Collection Requirements

Container:

Urine Container (URINE),

Sample Type:

See container

Minimum Collection Volume:

20mL

Collection Instructions:

Protect sample from light immediately following collection.

Processing Requirements

Alternate Containers:

Processing Instructions:

Minimum Assay Volume:

Stability:

Transport Instructions (to testing laboratory):

Send sample chilled and protected from light.

Testing Locations

Performed at:

Section	Department	Site	Contact Phone
Special Chemistry	Biochemistry	QEII Medical Centre	6383 4114

Last Updated : 02-03-2022 16:28