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HSV / VZV resistance testing
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General
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Clinical Use:
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Sequencing of the thymidine kinase (TK) gene of herpes simplex virus 1/2 or varicella zoster virus to identify mutations associated with resistance to aciclovir and related antivirals. Resistance testing may be considered when there is persistent HSV/VZV positivity despite appropriate treatment, or when there is active disease in an immunocompromised patient with prolonged prior exposure to antivirals.
Resistance testing is only performed after discussion with a Clinical Microbiologist and requires a specimen positive for HSV/VZV. |
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Availability:
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Testing is performed on request, with results usually available within 7 days of receipt by the testing lab. |
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Code:
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VHSTK |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Collection Requirements
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Container:
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Sample Type:
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Minimum Collection Volume:
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Collection Instructions:
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See 'HSV / VZV PCR' entry for suitable specimen types and other information. |
Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Minimum Assay Volume:
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Stability:
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7 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Molecular Diagnostics |
Microbiology |
QEII Medical Centre |
6383 4402 |
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Last Updated : 16-01-2024 11:35 |