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General
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Clinical Use:
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Autoantibodies to adrenal steroid 21-hydroxylase enzyme. Autoimmune adrenal disease (low cortisol, high ACTH).
The anti-adrenal cortex antibodies partly or fully block the enzyme converting 17-alpha-hydroxy-progesterone to 11-deoxy-cortisol, the precursor of cortisol. Positive results indicates isolated autoimmune Addison's disease or as part of a polyendocrine syndrome (thyroid disease, premature ovarian failure, diabetes mellitus (Type 1) and vitiligo. |
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Availability:
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Samples are batched and tested once a fortnight. |
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Aliases/Synonyms:
| 21-Hydroxylase Steroid Antibody, 21OHAA, |
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Code:
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21OH |
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Handling Instructions (to laboratory):
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Send separated sample frozen on dry ice. |
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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2mL |
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Collection Instructions:
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For advice: Contact QEII Immunology 6383 4306 |
Processing Requirements
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Alternate Containers:
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Serum, no gel (RED) |
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Processing Instructions:
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Centrifuge, separate and freeze sample. |
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Minimum Assay Volume:
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Stability:
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2 hours ambient |
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Transport Instructions (to testing laboratory):
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Send separated sample frozen on dry ice.
Requests should be reviewed by Immunologist prior to transport. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Laboratory |
SSWPS-Royal Prince Alfred Hospital |
(02) 9515 8279 |
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Last Updated : 19-12-2025 11:37 |