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General
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Clinical Use:
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Assessment of antibodies to GAD-65, IA2 +/- Znt8 is used for: evaluation of suspected type 1 diabetes; predicting risk of developing diabetes among relatives of patients with type 1 diabetes; predicting risk of future need for insulin treatment in adult-onset diabetic patients; predicting future risk of diabetes in women with gestational diabetes.
Patients will first be tested for antibodies to GAD-65 and IA2. For patients with positive GAD-65 and/or IA2 antibodies, no further testing will be performed. In patients where "diabetes antibodies" has been requested, antibodies to ZnT8 will be performed if GAD-65 and IA2 antibodies are negative.
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Availability:
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GAD and IA2 are tested fortnightly.
ZnT8 is tested fortnightly on samples with negative GAD and IA2 antibodies.
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Aliases/Synonyms:
| Diabetes Abs, Diabetes antibodies, GAD, IA2, ZnT8, |
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Code:
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DAA |
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Handling Instructions (to laboratory):
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory.
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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Serum |
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Minimum Collection Volume:
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4ml whole blood |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Processing Instructions:
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If request is for 'Diabetes Antibodies' please use DAA panel. |
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Minimum Assay Volume:
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200µl |
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Stability:
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Chilled; Frozen |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Immunology |
QEII Medical Centre |
6383 4306 |
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Last Updated : 30-05-2025 10:44 |