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Renal Phosphate Threshold (TmPi)
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General
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Clinical Use:
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This test is used to assess the renal tubular reabsorption of phosphate and to identify and differentiate between disorders of phosphate metabolism.
It can help to identify phosphaturia in patients with hypophosphataemia. A low TmPi suggests renal phosphate wasting, which may be seen with high activity of PTH or FGF-23 and in renal tubular disorders.
Increased TmPi may be seen with growth hormone excess, hypoparathyroidism or pseudohypoparathyroidism.
A paired blood and spot urine collection is required, preferably in the early morning and fasting state. |
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Availability:
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Samples are tested routinely during the testing laboratory's hours of operation. |
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Aliases/Synonyms:
| TmP/GFR, Tubular Maximum Reabsorption of Phosphate, |
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Code:
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TMPI |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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0d to <16y: 1.15 - 2.44 mmol/L GF
16y to <20y: 0.95 - 1.75 mmol/L GF
20y to 120y: 0.75 - 1.35 mmol/L GF
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Collection Requirements
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Container:
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Lithium Heparin-PST (GREEN), and, Urine Container (URINE), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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Collection Instructions:
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Samples are required to be collected in the early morning and patient must be fasting.
Blood and spot urine samples must be collected at the same time. |
Processing Requirements
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Alternate Containers:
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Serum Sep. Tube-SST (GOLD) |
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and |
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Urine Container (URINE) |
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Processing Instructions:
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Minimum Assay Volume:
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Stability:
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Core |
Biochemistry |
Fiona Stanley Hospital |
6152 8140 |
| Core |
Biochemistry |
Fremantle Hospital |
9431 2382 |
| Core |
Biochemistry |
QEII Medical Centre |
6383 4093 |
| Core |
Biochemistry |
Royal Perth Hospital |
9224 1176 |
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Last Updated : 15-08-2025 13:19 |