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General
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Clinical Use:
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Caerulplasmin is an alpha 2 serum glycoprotein produced by the liver. It is classed as an acute phase reactant produced with injured liver and in association with systemic illnesses (eg rheumatoid arthritis, cancer, bacterial infection, burns and MI). It can be increased in pregnancy, hyperthyroidism, aplastic anaemia, acute leukaemia and liver cirrhosis.
Caeruloplasmin is primarily ordered along with blood and/or urine copper tests to help diagnose Wilson's diesease, an inherited disorder associated with decreased levels of caeruloplasmin and excess storage of copper in the liver, brain, and other organs. Rarely, it may be ordered to help diagnose or differentiate between conditions associated with copper deficiencies. |
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Availability:
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Samples are batched and tested 3 times a week. |
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Aliases/Synonyms:
| Ceruloplasmin, |
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Code:
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CAER |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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| Age |
Lower Limit (g/L) |
Upper Limit (g/L) |
| 0 to <2m |
0.07 |
0.24 |
| 2m to <6m |
0.13 |
0.33 |
| 6m to <12m |
0.14 |
0.39 |
| 1Y to 18Y |
0.20 |
0.43 |
| 18Y to 120Y |
0.20 |
0.60 |
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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600uL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Lithium Heparin-PST (GREEN) |
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Processing Instructions:
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Centrifuge sample as soon as possible. |
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Minimum Assay Volume:
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130uL |
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Stability:
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3 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Core |
Biochemistry |
Fiona Stanley Hospital |
6152 8140 |
| Core |
Biochemistry |
QEII Medical Centre |
6383 4093 |
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Last Updated : 21-03-2023 15:21 |