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General |
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| Clinical Use: | Urinary histamine metabolites including 1-methyl-histamine and 1-methyl-imidazole acetic acid are raised in conditions where there is increased histamine turnover, and this is generally due to proliferation of Mast Cells or Basophils. 1-methylimidazole acetic acid is not currently being analysed, but 1-methyl histamine appears to have equivalent or improved sensitivity in detecting these disorders. | |||||
| Availability: | Samples are batched and tested once a week. | |||||
| Aliases/Synonyms: | 1 Methyl-Histamine, | |||||
| Code: | HIST | |||||
| Handling Instructions (to laboratory): | Send sample chilled. | |||||
| Hyperlink: | https://catalogue.pathology.health.nsw.gov.au/attachment/167daf94-9ed8-44d4-8e6c-b1ecadd06caa | |||||
| Unit of Measure: | Refer to reference interval | |||||
| Reference Interval: |
Refer to report or laboratory. |
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Collection Requirements |
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| Container: | UR24-HCL (UR24HCL), | |||||
| Sample Type: | See container | |||||
| Minimum Collection Volume: | ||||||
| Collection Instructions: | Sample must be kept refrigerated during collection. Special diet required for 24 hours before and during collection - Refer to hyperlink for details. 24hr urine HCL bottles can be requested from: QEII - 6383 4114 FSH - 6152 2830 Urine Histamine Specimen Collection Protocol |
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Processing Requirements |
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| Alternate Containers: |
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| Processing Instructions: | Refer to local manual for processing requirements. Freeze aliquot. |
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| Minimum Assay Volume: | 30mL | |||||
| Stability: | 3 days chilled | |||||
| Transport Instructions (to testing laboratory): | Send sample frozen on dry ice. | |||||
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Testing Locations |
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| Performed at: |
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Last Updated : 21-07-2026 09:02 |
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