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General |
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| Clinical Use: | Urinary histamine metabolites including 1-methyl-histamine and 1-methyl-imidazole acetic acid are raised in conditions where there is increased histamine turnover, and this is generally due to proliferation of Mast Cells or Basophils. 1-methylimidazole acetic acid is not currently being analysed, but 1-methyl histamine appears to have equivalent or improved sensitivity in detecting these disorders. | |||||||||
| Availability: | Samples are batched and tested once a week. | |||||||||
| Aliases/Synonyms: | 1 Methyl-Histamine, | |||||||||
| Code: | HIST | |||||||||
| Handling Instructions (to laboratory): | Send sample chilled. | |||||||||
| Hyperlink: | https://catalogue.pathology.health.nsw.gov.au/attachment/167daf94-9ed8-44d4-8e6c-b1ecadd06caa | |||||||||
| Reference Interval: |
Refer to report or laboratory. |
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Collection Requirements |
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| Container: | UR24-HCL (UR24HCL), | |||||||||
| Sample Type: | See container | |||||||||
| Minimum Collection Volume: | ||||||||||
| Collection Instructions: | Sample must be kept refrigerated during collection. Special diet required for 24 hours before and during collection - Refer to hyperlink for details. 24hr urine HCL bottles can be requested from PathWest QEII - 6383 4114. Urine Histamine Specimen Collection Protocol |
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Processing Requirements |
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| Alternate Containers: |
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| Processing Instructions: | Refer to local manual for processing requirements. Freeze aliquot. |
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| Minimum Assay Volume: | 30mL | |||||||||
| Stability: | 3 days chilled | |||||||||
| Transport Instructions (to testing laboratory): | Send sample frozen on dry ice. | |||||||||
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Testing Locations |
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| Performed at: |
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Last Updated : 19-12-2025 11:30 |
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