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General
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Clinical Use:
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MTX is a folic acid antagonist used in the treatment of acute lymphocytic leukemia,osteogenic sarcoma and other neoplasms. |
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Availability:
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Samples are tested routinely during the testing laboratory's hours of operation. |
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Aliases/Synonyms:
| MTX, |
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Code:
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MTX |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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CANCER THERAPY:
For a single bolus dose of methotrexate, potentially toxic concentrations are:
24 hours after dose > 5umol/L
48 hours after dose > 0.5umol/L
72 hours after dose > 0.05umol/L
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Collection Requirements
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Container:
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Lithium Heparin-PST (GREEN), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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0.5mL |
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Collection Instructions:
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If sample will not reach laboratory within 4 hours of collection, it must be centrifuged and separated from gel. Alternatively a non-gel tube should be used. |
Processing Requirements
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Alternate Containers:
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Serum Sep. Tube-SST (GOLD) |
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Lithium Heparin, No Gel (DKGNLITH) |
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Serum, no gel (RED) |
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Processing Instructions:
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Minimum Assay Volume:
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100uL |
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Stability:
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4 hours chilled (unseparated); 1 week chilled (separated) |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Core |
Biochemistry |
Fiona Stanley Hospital |
6152 8140 |
| Core |
Biochemistry |
QEII Medical Centre |
6383 4093 |
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Last Updated : 01-12-2022 16:40 |