Test Entry - Detail

SHBG

General

Clinical Use:

SHBG is synthesised in the liver and in the circulation it's biological function is the transport of sex-steroid hormones. It has a high binding affinity for testosterone and 5-dihydro-testosterone and lower affinity for 17beta-oestradiol. Approximately 44% of testosterone in normal adult males is bound to SHBG. In healthy women, the corresponding figure is about 66%, reaching 95% in late pregnancy. The relationship between the circulating concentrations of SHBG and testosterone is important in the evaluation of possible androgen excess in women who have hirsutism, acne or virilization, which may originate from excessive adrenal (eg Cushing's Syndrome) or ovarian (eg Polycyctic Ovarian Syndrome (PCOS)or ovarian tumour) androgen production.

Availability:

Samples are tested routinely during the testing laboratory's hours of operation.

Aliases/Synonyms:

Sex Hormone Binding Globulin, Sex Steroid Binding Protein, Testosterone-Oestradiol Binding Globulin ,

Code:

SHB

Handling Instructions (to laboratory):

Send sample chilled.

Hyperlink:

Reference Interval:

0 to <15d          10-50
15d to <4y         15-100
4y to <12y         35-150
Male
12y to <14y        25-150
14y to <17y        10-100
17y to <120y       10-70
Female
12y to <17y        25-150
17y to <120y       30-120

Collection Requirements

Container:

Serum Sep. Tube-SST (GOLD),

Sample Type:

See container

Minimum Collection Volume:

1mL

Collection Instructions:

Processing Requirements

Alternate Containers:

Serum, no gel (RED)

Lithium Heparin-PST (GREEN)

Processing Instructions:

Minimum Assay Volume:

200uL

Stability:

2 weeks chilled; 2 months frozen

Transport Instructions (to testing laboratory):

Send sample chilled.

Testing Locations

Performed at:

Section	Department	Site	Contact Phone
Core	Biochemistry	QEII Medical Centre	6383 4093
Special Chemistry	Biochemistry	Fiona Stanley Hospital	6152 2830

Last Updated : 15-01-2024 08:23