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General
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Clinical Use:
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It is well established that Vitamin D nutritional status is a function of circulating 25-Hydroxyvitamin D (25-OH-D). The measurement of 25-OH-D as a clinical assessment of nutritional vitamin D deficiency has become important in the management of clinical bone disease. The two major forms of 25-OH-D are cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2). Vit D3 is derived mainly from actions of UV light on the skin while D2 is derived solely from dietary sources. Since these two parent compounds provide various contributions to the overall vitamin D status of the individual, it is important that both forms are measured equally. The measurement of 25-OH-D is becoming increasingly important in the management of patients with various disorders of calcium metabolism associated with rickets, neonatal hypocalcaemia, pregnancy, nutritional and renal osteodystrophy, hypoparathyroidism and postmenopausal osteoporosis. |
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Availability:
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VTD: Samples are tested routinely during the testing laboratory's hours of operation.
LCMS Assay: Samples are batched and tested once a week.
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Aliases/Synonyms:
| 25 (OH) Vit D, 25-Hydroxycholecalciferol, 25-Hydroxyvitamin D, 25-OH Cholecalciferol, D3 (25-Hydroxyvitamin D), |
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Code:
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VTD: VTD / LCMS: VTDLC |
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Handling Instructions (to laboratory):
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Send sample chilled.
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Hyperlink:
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Reference Interval:
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>50 nmol/L
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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1mL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Serum, no gel (RED) |
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Lithium Heparin, No Gel (DKGNLITH) |
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Lithium Heparin-PST (GREEN) |
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Processing Instructions:
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If a sample other than serum is received, please forward to the testing department to determine sample suitability.
Forward sample to FSH for LCMS confirmation. |
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Minimum Assay Volume:
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250uL |
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Stability:
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7 days chilled; 9 weeks frozen |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Core |
Biochemistry |
Fiona Stanley Hospital |
6152 8140 |
| Core |
Biochemistry |
QEII Medical Centre |
6383 4093 |
| Core |
Biochemistry |
Royal Perth Hospital |
9224 1176 |
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Last Updated : 15-03-2023 13:28 |