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Anti-Neutrophil Cytoplasmic Antibody
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General
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Clinical Use:
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Anti-neutrophil cytoplasmic antibody (ANCA), is a first-line screening test used in the assessment of patients with suspected ANCA-associated vasculitis comprising granulomatous polyangiitis (GPA vasculitis), eosinophilic granulomatosis with polyangiitis (EGPA vasculitis) and microscopic polyangiitis (MPA vasculitis).
Positive ANCA may also be seen in non-vasculitic conditions, such as inflammatory bowel disease, liver disease, cystic fibrosis, rheumatoid and psoriatic arthritis.
A positive ANCA screening test will be routinely followed by second-line testing for MPO and PR3 antibodies which are more specific confirmatory tests for the ANCA-associated vasculitides. |
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Availability:
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Samples are batched and tested twice a week.
Please contact testing laboratory for urgent requests. |
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Aliases/Synonyms:
| ANCA, Anti-Neutrophil Cytoplasmic Autoantibody, Neutrophil Cytoplasmic Autoantibody, Vasculitis Screen, |
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Code:
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ANCA |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Minimum Assay Volume:
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200uL |
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Stability:
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7 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Immunology |
Fiona Stanley Hospital |
6152 8006 |
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Immunology |
QEII Medical Centre |
6383 4306 |
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Last Updated : 12-06-2025 09:34 |