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General
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Clinical Use:
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Gabapentin is an antiepileptic which is used to treat seizures, bipolar disorder, migraines, neuropathic pain and neuromuscular disorders.
Because gabapentin does not bind to serum proteins and is not metabolized by the liver, it does not exhibit pharmacokinetic interactions with other antiepileptic drugs; its serum concentration is not changed following the addition or discontinuation of other common anticonvulsants (e.g., Phenobarbital, phenytoin, carbamazepine, valproic acid), nor is their serum concentration altered upon adding or discontinuing gabapentin.
Ref: Mayo Laboratories Test Catalog. |
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Availability:
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Samples are batched and tested once a week. |
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Aliases/Synonyms:
| Neurontin, |
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Code:
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GABA |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Therapeutic range 2-20 mg/L. Toxic Range: > or =25.0 mg/mL.
Therapeutic range is 2 to 20mg/L. Toxicity may be seen for concentrations of gabapentin exceeding 25mg/L.
Correlation between concentration and clinical effect not well established.
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Collection Requirements
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Container:
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Serum, no gel (RED), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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Collection Instructions:
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Collect sample prior to dose as trough level.
Record date, time and dosage of last dose on request form. |
Processing Requirements
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Alternate Containers:
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Lithium Heparin, No Gel (DKGNLITH) |
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Processing Instructions:
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Centrifuge and separate sample. |
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Minimum Assay Volume:
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1mL |
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Stability:
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Laboratory |
SSWPS-Royal Prince Alfred Hospital |
(02) 9515 8279 |
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Last Updated : 08-10-2020 07:49 |