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General
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Clinical Use:
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Histones are nuclear proteins which are bound to DNA and form an integral part of the chromatin structure. Antibodies to histones occur in the sera of approximately 90% of patients with drug-induced SLE, while patients with naturally-occurring (idiopathic) SLE can have anti-histone antibodies in addition to a variety of other anti-nuclear antibodies. Rheumatoid arthritis patients occasionally develop anti-histone antibodies as well as other ANA. In contrast, drug-induced SLE is marked by the appearance of mainly anti-histone antibodies. |
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Availability:
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Aliases/Synonyms:
| Anti-Histone Antibody, Histone Autoantibody, |
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Code:
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ENAH |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Refer to report or laboratory
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Processing Instructions:
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Minimum Assay Volume:
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100uL |
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Stability:
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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Immunology |
Fiona Stanley Hospital |
6152 8006 |
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Immunology |
QEII Medical Centre |
6383 4306 |
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Last Updated : 01-10-2020 11:37 |