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Free Light Chains (Serum)
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General
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Clinical Use:
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Immunoglobulin molecules consist of 2 identical heavy chain (G, A, M, D or E) and 2 identical light chain molecules (kappa or lambda). In healthy individuals the majority of these light and heavy chains are linked together, with a low concentration of free circulating light chains. Elevated serum levels of monoclonal free light chains are associated with malignant plasma cell proliferation (eg multiple myeloma), primary amyloidosis and light chain deposition disease. Raised serum levels of polyclonal light chains may be associated with autoimmune diseases such as SLE. |
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Availability:
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Samples are tested Monday-Friday. |
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Aliases/Synonyms:
| Free Kappa Light Chains, Free Lambda Light Chains, LCR, Light Chain Restriction, Serum Free Light Chains, SFLC, |
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Code:
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SLC |
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Handling Instructions (to laboratory):
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Send sample chilled. |
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Hyperlink:
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Reference Interval:
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Free kappa 3.3 to 19.4 mg/L
Free lambda 5.7 to 26.3 mg/L
Ratio 0.26 to 1.65
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Collection Requirements
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Container:
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Serum Sep. Tube-SST (GOLD), |
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Sample Type:
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See container |
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Minimum Collection Volume:
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3mL |
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Collection Instructions:
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Processing Requirements
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Alternate Containers:
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Serum, no gel (RED) |
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Processing Instructions:
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Centrifuge and separate sample. |
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Minimum Assay Volume:
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1mL |
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Stability:
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7 days chilled |
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Transport Instructions (to testing laboratory):
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Send sample chilled. |
Testing Locations
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Performed at:
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Section
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Department
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Site
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Contact Phone
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| Special Chemistry |
Biochemistry |
Fiona Stanley Hospital |
6152 2830 |
| Special Chemistry |
Biochemistry |
QEII Medical Centre |
6383 4114 |
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Last Updated : 21-02-2025 08:27 |